What You Need To Know About Fertility Treatments: After Age 40

Getting pregnant after 40 is extremely problematic. This isn’t surprising, given that the challenges of getting pregnant after 40 have been well documented in both scientific research and popular culture. While it has its drawbacks, getting pregnant in your 40s isn’t the end-all solution to your family-building quest that you may have been led to believe.

In this post, we’ll look at the possibilities of getting pregnant beyond 40, why fertility declines, what you can do to naturally reverse this decline and improve egg quality, and a variety of fertility treatments including fallopian tubes treatment. 

How Does Egg Quality Affect Fertility and IVF?

The quality of the egg is the most important component in determining the embryo’s quality. The chromosomal condition of the egg plays a large role in the “egg quality” equation. With increasing female age, the rate of chromosomal defects in eggs (and thus embryos) grows considerably. Around 30% of eggs are chromosomally defective by the age of 30. Around 60% of people are aberrant by the age of 40, and 90% are abnormal by the age of 44.

Before transferring embryos to the uterus, preimplantation genetic testing for aneuploidy (PGT-A) can be done to check for chromosomally normality (euploidy). After PGT-A, embryos with normal chromosomal analysis have a very high chance of implantation and live birth.

1. Fertility Treatment for Over 40

Fertility therapies such as intrauterine insemination (IUI), fertility medications, and in vitro fertilization (IVF) are all affected by age.

According to data, the success rate of using fertility medicines with intrauterine insemination in women over 40 is often less than 5% per cycle.

2. Treating Infertility with IVF after 40

For women in their 40s, in vitro fertilization (IVF) is more effective. For women over 40, the IVF success rate for fresh embryos from non-donor eggs is 24 percent at HRC Fertility centers.

3. Trying to Conceive over Age 40

The chances of a woman over 40 getting pregnant spontaneously is just approximately 5% per month. Infertility affects 29 percent of women aged 40 to 44, compared to 15 percent of women aged 30 to 34 and 7% of women aged 20 to 24.

The eggs in your ovaries age with you and are more likely to have genetic abnormalities as you become older. A woman in her 40s, for example, has a 1 in 106 probability of having a baby with Down Syndrome, whereas a woman in her 35s has a 1 in 378 possibilities.

Not only is it more difficult to become pregnant in your 40s, but your chances of miscarriage are also increased. A woman’s chance of miscarriage is ten percent between the ages of 20 and 24, twelve percent between the ages of 30 and 34, thirty-four percent between the ages of 40 and 44, and fifty-three percent between the ages of 45 and fifty-five.